Introduction
Pathology is the backbone of modern medical diagnosis. From routine blood tests to advanced histopathological analysis, accurate laboratory investigation plays a critical role in patient care. In a rapidly growing healthcare system like Bangladesh, the demand for skilled pathology professionals is increasing every year. For students and graduates who want to build a strong and practical career in laboratory medicine, enrolling in a Pathology Internship in Dhaka is one of the most important steps.

HRTD Medical Institute, located in Mirpur, Dhaka, has emerged as a trusted name in medical and diagnostic education. Our pathology internship program is designed to bridge the gap between theoretical knowledge and real-world laboratory practice. This detailed guide explains everything you need to know about pathology internships in Dhaka, with a special focus on the structured, career-oriented training offered by HRTD Medical Institute.
Understanding Pathology and Its Importance
Pathology is the branch of medical science that studies the causes and effects of diseases through the examination of organs, tissues, body fluids, and laboratory samples. It supports almost every medical specialty, including internal medicine, surgery, gynecology, pediatrics, oncology, and infectious disease management.
In clinical practice, physicians depend heavily on pathology reports for accurate diagnosis, treatment planning, and disease monitoring. A well-trained pathology professional ensures reliability, accuracy, and ethical handling of laboratory results. This is why hands-on internship training is essential for anyone pursuing a career in pathology.
Why a Pathology Internship Is Essential
Classroom education provides fundamental concepts, but pathology is a highly practical discipline. Without real laboratory exposure, it is impossible to gain confidence and professional competence. A pathology internship allows students to:
- Apply theoretical knowledge in real diagnostic settings
- Learn proper sample collection, handling, and processing
- Operate laboratory instruments safely and accurately
- Understand quality control and laboratory ethics
- Communicate effectively with doctors and healthcare teams
In Dhaka, where diagnostic laboratories operate under high patient load, an internship provides invaluable experience that cannot be replaced by textbooks alone.
Scope of Pathology Internship in Dhaka
Dhaka is the center of healthcare services in Bangladesh. Government hospitals, private diagnostic centers, medical colleges, and specialized laboratories offer vast opportunities for pathology interns. With the growing awareness of preventive healthcare, laboratory testing has increased significantly, creating strong demand for trained pathology professionals.
A pathology internship in Dhaka prepares students for careers such as:
- Medical Laboratory Technologist
- Pathology Lab Assistant
- Diagnostic Center Technician
- Research Laboratory Assistant
- Hospital Laboratory Officer
Graduates with internship experience are highly preferred by employers due to their practical skills and workplace readiness.
About HRTD Medical Institute
HRTD Medical Institute is a reputed medical education and training institute located at:
Section-6, Block-Kha, Road-1, Plot-11, Metro Rail Pillar-249, Folpotti Mosque Lane, Mirpur-10, Dhaka-1216
With years of experience in medical training, HRTD Medical Institute is committed to producing skilled, ethical, and job-ready healthcare professionals. Our pathology internship program is carefully structured to meet industry standards and real diagnostic laboratory requirements.

Pathology Internship Program at HRTD Medical Institute
The Pathology Internship in Dhaka offered by HRTD Medical Institute is designed for students who have completed or are pursuing pathology-related academic programs. This internship focuses on hands-on laboratory work under the supervision of experienced instructors and professional technologists.
Program Objectives
The primary objectives of the internship are:
- To develop strong practical laboratory skills
- To ensure understanding of diagnostic procedures
- To train students in modern laboratory technologies
- To promote professionalism, accuracy, and ethical practice
Departments Covered During Internship
The pathology internship at HRTD Medical Institute provides rotational training across major laboratory departments:
1. Hematology
Interns learn complete blood count (CBC), ESR, blood grouping, coagulation tests, and peripheral blood smear examination. Emphasis is given to automated analyzers as well as manual techniques.
2. Clinical Biochemistry
Training includes blood glucose, lipid profile, liver function tests (LFT), kidney function tests (KFT), electrolyte analysis, and enzyme assays. Interns gain experience using modern biochemical analyzers.
3. Microbiology
Students learn specimen collection, staining techniques, culture and sensitivity testing, and identification of common pathogens. Infection control and biosafety are strongly emphasized.
4. Histopathology
Interns are trained in tissue processing, embedding, microtomy, staining (H&E), and slide preparation. This section provides insight into cancer diagnosis and tissue-based disease analysis.
5. Immunology and Serology
Training includes ELISA, rapid test kits, and immunological assays used in detecting infectious and autoimmune diseases.

Duration and Structure of the Internship
The pathology internship program at HRTD Medical Institute is flexible and designed according to students’ academic background and career goals. Internship duration may range from 3 months to 12 months.
The structure includes:
- Orientation and laboratory safety training
- Department-wise practical rotation
- Daily hands-on laboratory work
- Case-based learning and discussions
- Performance evaluation and feedback
Eligibility Criteria
Students eligible for the pathology internship in Dhaka at HRTD Medical Institute include:
- Diploma in Pathology students or graduates
- Medical Technology (Lab) students
- Science background students interested in laboratory careers
- Healthcare professionals seeking practical pathology exposure
Basic knowledge of biology and laboratory science is preferred.
Learning Environment and Facilities
HRTD Medical Institute provides a professional and student-friendly learning environment. Our laboratories are equipped with modern instruments and follow standard operating procedures (SOPs).
Facilities include:
- Well-equipped pathology laboratories
- Modern diagnostic instruments
- Experienced instructors and supervisors
- Small batch sizes for personalized training
- Emphasis on laboratory safety and quality control
Career Benefits of Internship from HRTD Medical Institute
Completing a pathology internship from HRTD Medical Institute offers multiple career advantages:
- Strong practical skills recognized by employers
- Increased job opportunities in diagnostic centers
- Confidence to work independently in laboratories
- Professional certification and internship experience
- Career guidance and job support
Our alumni are working successfully in hospitals, clinics, and diagnostic laboratories across Bangladesh.
Why Choose HRTD Medical Institute for Pathology Internship in Dhaka
There are many institutes offering training, but HRTD Medical Institute stands out due to:
- Practical, hands-on focused training
- Experienced faculty and lab technologists
- Updated curriculum based on current diagnostic practices
- Affordable internship fees
- Convenient location in Mirpur, Dhaka
We believe in quality education that leads to real career success.
Future Scope of Pathology Career in Bangladesh
With the expansion of healthcare services, private hospitals, and diagnostic centers, the scope of pathology professionals in Bangladesh is very promising. Preventive health checkups, chronic disease monitoring, and advanced diagnostic technologies are increasing the demand for skilled laboratory personnel.
Students who complete a pathology internship in Dhaka from a reputed institute like HRTD Medical Institute are well-positioned to build stable and rewarding careers in the healthcare sector.
Conclusion
A Pathology Internship in Dhaka is a crucial step for anyone aiming to build a successful career in diagnostic and laboratory medicine. It transforms academic knowledge into professional competence and prepares students for real-world challenges.
HRTD Medical Institute is dedicated to providing high-quality pathology internship training that meets industry demands and supports students’ long-term career goals. Through structured practical exposure, experienced guidance, and a professional learning environment, we help shape the future of skilled pathology professionals in Bangladesh.
If you are looking for a reliable, practical, and career-oriented pathology internship in Dhaka, HRTD Medical Institute is the right choice for you.
Some Practical of the Pathology internship
- Blood collection procedure
- Blood grouping
- Cross matching
- Liver function test(SGPT,SGOT)
- kidney function test(serum creatinine, serum urea, Uric acid)
- Lipid profile ( Total cholesterol, LDL, HDL, Triglyceride)
- Urine R/E
- Bleeding time
- Clotting time
- Fasting blood glucose
- Random blood glucose
- Oral glucose tolerance test
- Blood film for CBC test
- Total protein
- ESR
- Serum iron
- Serum Bilirubin
- Hemoglobin
- Thyroid function test (TSH,T3,T4)
- Troponin I
- Vitamin D
- Prolactin hormone
- Dengue NS1
- Dengue IgG and IgM
- Widal test for typhoid fever
- Kala jor
- Chikungunya test
- Malaria
- Prostate specific antigen (PSA)
- Calcium
- CRP
- VDRL
- HBS-Ag
- Anti HCV
- Anti HIV
- ASO
- RA
- Anti H pylori
- Manteaux test
- IgE and many other test
Blood collection procedure
A blood collection procedure, usually venipuncture, involves preparing the patient, applying a tourniquet, selecting and cleaning a vein (often in the inner elbow), inserting a needle at a shallow angle (around 30°), collecting blood into tubes (releasing the tourniquet first), and applying pressure to the site afterward with gauze until bleeding stops, all while maintaining sterile technique and proper labeling.
Key Steps for Venipuncture (Most Common Method)
- Preparation & Patient ID:
- Verify patient and test info, perform hand hygiene, and explain the process.
- Have the patient sit or lie down comfortably, with the arm supported below heart level.
- Equipment & Site Selection:
- Gather necessary sterile equipment (needle, tubes, tourniquet, antiseptic, gauze).
- Apply the tourniquet 4-5 finger-widths above the chosen site (inner arm bend) and ask the patient to make a fist.
- Palpate (feel) for a strong, bouncy vein; don’t re-touch the area after cleaning.
- Puncture & Collection:
- Clean the site with 70% isopropyl alcohol and let it air dry completely.
- Anchor the vein by pulling skin taut below the site with your thumb.
- With the needle’s bevel (opening) facing up, insert it swiftly into the vein at a 15-30° angle.
- Once blood flows, release the tourniquet (before two minutes) and slowly pull back the syringe plunger or push the vacutainer tube onto the needle.
- Fill tubes in the correct order, inverting them gently to mix if needed (e.g., EDTA tubes).
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Blood grouping
Blood grouping classifies blood into types (A, B, AB, O) based on specific antigens (proteins) on red blood cells and antibodies in plasma, combined with the presence or absence of the Rh factor, creating eight main groups (A+, A-, B+, B-, O+, O-, AB+, AB-) crucial for safe blood transfusions, as receiving incompatible blood can be fatal. O negative is the universal donor, and AB positive is the universal recipient, due to their lack of A/B antigens or antibodies, respectively, allowing them to mix with most other types.
The ABO System (Antigens & Antibodies)
- Blood Group A: Has A antigens on red cells, anti-B antibodies in plasma.
- Blood Group B: Has B antigens on red cells, anti-A antibodies in plasma.
- Blood Group AB: Has both A and B antigens, but no antibodies.
- Blood Group O: Has neither A nor B antigens, but both anti-A and anti-B antibodies.
The Rh Factor (Positive/Negative)
- Rh Positive (+): Has the Rh protein (D antigen) on red blood cells.
- Rh Negative (-): Lacks the Rh protein.
Compatibility & Transfusions
- Universal Donor: O Negative (O-) can donate to anyone because it lacks A, B, and Rh antigens, so recipients don’t form antibodies against it.
- Universal Recipient: AB Positive (AB+) can receive from anyone because it has A, B, and Rh antigens, meaning it already has antibodies for those types.
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Liver function test
A Liver Function Test (LFT) is a panel of blood tests measuring enzymes, proteins, and substances like ALT, AST, ALP, GGT, bilirubin, and albumin to assess liver health, detect damage or disease (like hepatitis, cirrhosis, or blockages), monitor treatment effectiveness, and check for medication side effects, providing a comprehensive view of how well the liver is working by checking levels of these liver-produced or liver-related chemicals.
What it checks
- Liver Enzymes (ALT, AST, ALP, GGT): Elevated levels often signal liver cell damage or inflammation, with specific patterns suggesting different issues (e.g., GGT helps differentiate liver/bone issues).
- Bilirubin: A yellow pigment; high levels can indicate liver disease or bile duct blockage.
- Albumin & Total Protein: Measures the liver’s ability to produce proteins crucial for bodily functions.
- Prothrombin Time (PT/INR): Checks how quickly blood clots, as the liver produces clotting factors; prolonged time suggests impaired function.
Why it’s done
- Screening: To check for liver disease in at-risk individuals (heavy drinkers, obese, diabetic).
- Diagnosis: To find the cause of symptoms like jaundice, abdominal pain, or fatigue.
- Monitoring: To track the progression of liver disease or treatment response.
- Medication Safety: To ensure certain drugs aren’t harming the liver.
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kidney function test
A kidney function test (KFT) uses blood and urine tests to check how well your kidneys filter waste, balancing fluids and minerals. Key blood tests measure waste products like Creatinine (used to calculate eGFR), Blood Urea Nitrogen (BUN), and electrolytes, while urine tests look for protein or glucose. These help diagnose kidney disease, monitor existing conditions (like diabetes/high BP), or check medication effects, with imaging (ultrasound) or biopsy used for deeper investigation.
Common Blood Tests
- Creatinine: A waste product from muscle breakdown; high levels suggest poor filtering.
- eGFR (Estimated Glomerular Filtration Rate): Calculated from creatinine, age, sex, etc., showing overall kidney filtering efficiency (higher is better).
- BUN (Blood Urea Nitrogen): Measures urea, another waste product; elevated levels can signal kidney issues.
- Electrolytes: Sodium, potassium, chloride, bicarbonate levels help check fluid balance.
Common Urine Tests
- Urinalysis: Checks for protein (albumin), glucose, blood, and other signs of damage.
- Albumin-to-Creatinine Ratio (ACR): Detects small amounts of albumin, an early sign of damage.
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Lipid profile
A lipid profile is a blood test that measures fats (lipids) in your blood, including total cholesterol, “good” HDL, “bad” LDL, VLDL, and triglycerides, to assess your risk of cardiovascular disease (heart attack, stroke) by checking for plaque buildup in arteries. It helps doctors monitor heart health, guide lifestyle changes, and manage conditions like high cholesterol, often requiring a 9-12 hour fast beforehand for accurate results.
Key components measured:
- Total Cholesterol: All cholesterol in your blood.
- LDL (Low-Density Lipoprotein): “Bad” cholesterol that can clog arteries.
- HDL (High-Density Lipoprotein): “Good” cholesterol that removes LDL from your body.
- Triglycerides: A type of fat from food, used for energy; high levels increase heart risk.
- VLDL (Very Low-Density Lipoprotein): Transports triglycerides and can also build up in vessels.
Purpose of the test:
- Assess Risk: Determine your risk for heart disease, stroke, and atherosclerosis (plaque buildup).
- Monitor Treatment: Check if diets or medications are effectively lowering cholesterol.
- Screening: Often done during routine physicals to catch issues early, as high lipids often have no symptoms.
Urine R/E
“Urine re” usually refers to a Urine Routine Examination (RE), also called Urinalysis, a common test checking urine’s appearance, concentration, and content (physical, chemical, microscopic) for UTIs, kidney/liver disease, diabetes, or general health, often paired with a CS (Culture & Sensitivity) for infection-causing microbes. It involves checking color, pH, specific gravity, and looking for cells, bacteria, or crystals, helping diagnose issues like kidney stones, infections, or metabolic disorders.
What it checks (RE/ME)
- Routine Examination (RE): Physical & Chemical aspects (Color, clarity, pH, protein, glucose, etc.).
- Microscopic Examination (ME): Microscopic view for Red/White Blood Cells, bacteria, crystals, casts.
- Culture & Sensitivity (CS): Grows bacteria to identify the specific microbe and best antibiotic.
Why it’s done
- Routine check-ups: General health screening.
- Symptom investigation: Painful urination, blood in urine, abdominal/back pain.
- Diagnosis: Kidney disease, diabetes, liver disease, UTIs, kidney stones.
- Monitoring: Tracking disease progression or pre-surgery.
How to give a sample (Mid-Stream Urine – MSU)
- Wash genitals thoroughly.
- Start urinating into the toilet.
- Collect 10-20 ml of the mid-stream (middle part) urine in a sterile container.
- Send to the lab quickly or refrigerate for a short time.
Bleeding time
Bleeding time (BT) is a medical test measuring how long it takes for a small skin cut to stop bleeding, assessing primary hemostasis (platelet plug formation) and vessel function, with normal times generally 3-10 minutes, though it’s less common now due to poor specificity. Prolonged times suggest platelet issues (like low count or poor function), vascular problems, or certain meds (aspirin) and can indicate conditions like thrombocytopenia, Von Willebrand disease, or liver disease, while shortened times usually aren’t significant.
How it’s Performed (Ivy Method Example)
- A blood pressure cuff is inflated on the upper arm to maintain steady pressure.
- Two small, shallow cuts are made on the forearm.
- The cuff is deflated.
- Filter paper blotted to the cuts every 30 seconds until bleeding stops.
- The total time is recorded.
What it Shows
- Normal: 3 to 10 minutes (varies by method).
- Prolonged: Suggests issues with platelet function, platelet count (e.g., thrombocytopenia), blood vessel integrity, or medications like aspirin.
- Conditions: Can point to von Willebrand disease, liver disease, or certain blood disorders.
Blood glucose
Blood glucose, or blood sugar, is the main sugar in your blood, your body’s primary energy source from food (especially carbs). It’s regulated by insulin, a hormone that moves glucose into cells; imbalances can signal diabetes (high levels) or hypoglycemia (low levels). Monitoring these levels, often with a meter, helps manage conditions like diabetes and prevents long-term complications by keeping levels in a target range (e.g., fasting <100 mg/dL, 2 hrs post-meal <180 mg/dL).
What it is
- Energy Source: Glucose is your cells’ main fuel, carried in the bloodstream from the food you eat (fruits, bread, pasta).
- Hormonal Control: Insulin (from the pancreas) helps cells absorb glucose; glucagon releases stored glucose when levels are low.
Why it matters
- Diabetes: High blood sugar (hyperglycemia) occurs when the body doesn’t produce enough insulin or use it effectively, leading to diabetes.
- Complications: Consistently high glucose damages blood vessels and nerves, increasing risks for heart disease, kidney issues, and eye problems.
Normal vs. High Levels (General Guidelines)
- Fasting (no food for 8+ hrs): Under 100 mg/dL (5.6 mmol/L) is normal; 100-125 mg/dL is prediabetes; 126 mg/dL+ is diabetes, says the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- 2 Hours After a Meal: Under 180 mg/dL (10 mmol/L) is a typical target for people with diabetes, notes MedlinePlus.
Total protein
Total protein refers to the overall amount of protein in your blood, a key indicator of health measured by a blood test, combining two main types: albumin (for fluid balance, transport) and globulins (for immune function, transport). Levels help diagnose liver, kidney issues, or malnutrition, indicating if your body makes too much or too little, with abnormal levels often needing further tests like the A/G ratio.
What it measures
- Albumin: The most abundant protein, preventing fluid leaks from vessels and carrying hormones, vitamins, and fats.
- Globulins: A group including antibodies (gamma globulins) for immunity, plus alpha and beta globulins for transport.
Why it’s tested
- To check liver and kidney function.
- To help diagnose malnutrition or nutritional deficiencies.
- To investigate symptoms like swelling, fatigue, or frequent infections.
- To monitor chronic diseases.
ESR
ESR usually stands for Erythrocyte Sedimentation Rate, a common blood test measuring how fast red blood cells (erythrocytes) settle in a tube, indicating inflammation in the body, often from infections, autoimmune issues, or other conditions. Faster settling (higher ESR) means more inflammation, as cells clump together and get heavier; it helps monitor disease but doesn’t diagnose a specific cause. ESR also refers to the European Society of Radiology, a professional organization for medical imaging.
Erythrocyte Sedimentation Rate (Blood Test)
- What it is: A test measuring how quickly red blood cells (RBCs) fall to the bottom of a test tube.
- How it works: Inflammation causes proteins to make RBCs clump, making them heavier and sink faster.
- What it shows: A high ESR signals inflammation, but it’s non-specific, meaning it doesn’t pinpoint the exact disease.
- When it’s used: To detect inflammation from infections, autoimmune diseases (like lupus, rheumatoid arthritis), and cancers, and to monitor chronic conditions.
Serum Bilirubin
Serum bilirubin is a blood test measuring a yellow pigment from red blood cell breakdown, crucial for checking liver function, diagnosing jaundice, bile duct issues, or blood disorders like hemolytic anemia, with levels indicating how well the liver processes bilirubin, as high levels can signal disease but also have protective antioxidant roles. The test measures total bilirubin (direct + indirect) and helps doctors see if your liver is healthy or struggling, often alongside other liver tests.
What it is
- Bilirubin: A yellowish substance produced when old red blood cells break down.
- Liver’s Role: A healthy liver processes bilirubin for excretion in bile, but if the liver’s struggling or blocked, bilirubin builds up in the blood.
Why the test is done
- Diagnose Jaundice: Yellow skin/eyes.
- Check Liver Health: Signs of hepatitis, cirrhosis, or drug damage.
- Find Bile Duct Blockages: From gallstones or tumors.
- Monitor Blood Disorders: Conditions where red blood cells break down too fast (like hemolytic anemia).
- Newborn Jaundice: To see if newborns need treatment (phototherapy).
Types of Bilirubin Measured
- Total Bilirubin: Sum of direct and indirect.
- Indirect (Unconjugated): Bilirubin before it’s processed by the liver.
- Direct (Conjugated): Bilirubin after it’s processed by the liver.
What high levels can mean (Hyperbilirubinemia)
- Liver disease (hepatitis, cirrhosis).
- Bile duct obstruction.
- Excessive red blood cell destruction (hemolysis).
What low levels can mean (Hypobilirubinemia)
- Often not a problem; possibly caffeine or certain medications.
- May be linked to some autoimmune diseases or better cardiovascular health.
Normal Ranges (Adults)
- Total: Roughly 0.1 to 1.2 mg/dL (varies by lab).
- Direct: Around 0.1 to 0.3 mg/dL.
- Indirect: Around 0.2 to 0.8 mg/dL.
Thyroid function test
A thyroid function test (TFT) is a blood test checking Thyroid-Stimulating Hormone (TSH), T4 (thyroxine), and sometimes T3 (triiodothyronine) levels to see how well your thyroid gland in your neck is working, helping diagnose conditions like hypothyroidism (underactive) or hyperthyroidism (overactive), or to monitor treatment. The TSH test is usually first, with high TSH often signaling an underactive thyroid and low TSH an overactive one, but T4 and T3 levels confirm the diagnosis.
Key Tests Included in a Thyroid Panel:
- TSH (Thyroid-Stimulating Hormone): The most common first test, measuring the hormone from the pituitary gland that tells the thyroid to produce hormones. High TSH means the thyroid isn’t making enough (underactive); low TSH means it’s overproducing (overactive).
- Free T4 (Free Thyroxine): Measures the main thyroid hormone circulating in your blood, showing how much the gland is actively producing.
- Free T3 (Free Triiodothyronine): Measures the active form of thyroid hormone; often checked if hyperthyroidism is suspected.
Why It’s Done:
- To diagnose thyroid disorders (hypo/hyperthyroidism).
- To monitor treatment, like hormone replacement therapy.
- To investigate symptoms like fatigue, weight changes, mood swings, or changes in heart rate.
What to Expect:
- A simple blood draw from a vein in your arm.
How Results Are Interpreted (General Guide):
- Hypothyroidism (Underactive): High TSH, Low Free T4/T3.
- Hyperthyroidism (Overactive): Low TSH, High Free T4/T3.
- Subclinical Hypothyroidism: High TSH, but normal T4/T3 levels.
Vitamin D
Vitamin D, often called the “sunshine vitamin,” is a fat-soluble nutrient crucial for calcium absorption, strong bones, muscle function, and immune health, produced by skin exposure to sunlight but also obtained from fatty fish, fortified foods, and supplements. Deficiency can lead to bone diseases like rickets (children) or osteomalacia (adults), so many people, especially in winter or with low sun exposure, need supplements, while some foods (milk, cereals) are fortified, and sunlight remains a key source.
Key Functions
- Bone Health: Helps absorb calcium and phosphorus for building and maintaining strong bones and teeth, preventing rickets and osteoporosis.
- Immune Support: Supports the immune system to fight infections.
- Muscle & Nerve Function: Essential for muscle movement and nerve communication.
Sources
- Sunlight: Skin produces Vitamin D3 when exposed to UVB rays, but this varies by season, location, skin type, and time of day.
- Foods: Fatty fish (salmon, mackerel), egg yolks, red meat, liver, and fortified foods like milk, cereals, and plant-based milks.
- Supplements: Available as D2 (ergocalciferol) and D3 (cholecalciferol).
Deficiency & Risk Factors
- Risks: People with dark skin, older adults, those with low sun exposure (due to work, location, clothing), and certain medical conditions.
- Symptoms: Bone pain, weak bones.
Prolactin hormone
Prolactin is a hormone from the pituitary gland essential for breast development and milk production (lactation) in women, but it affects many body functions in both sexes, including reproduction and metabolism. Levels naturally rise during pregnancy, but high levels (hyperprolactinemia) can cause irregular periods, infertility, low libido, erectile dysfunction, and unexpected milk production (galactorrhea). Causes of high prolactin include pituitary tumors (prolactinomas), hypothyroidism, stress, certain medications, and kidney/liver disease, with dopamine (a neurotransmitter) usually inhibiting its release.
Key Functions
- Lactation: Stimulates milk production in new mothers.
- Reproduction: Affects ovarian function in women and testicular function in men, influencing fertility and sexual function.
- Other Roles: Involved in metabolism, immune system regulation, and other bodily processes.
Causes of High Prolactin (Hyperprolactinemia)
- Pituitary Tumors: Benign tumors called prolactinomas.
- Medical Conditions: Hypothyroidism, kidney or liver disease, chest injuries, shingles.
- Medications: Antidepressants, antipsychotics, blood pressure drugs, opioids.
- Physiological: Stress, sleep, exercise, nipple stimulation, eating.
Symptoms of High Prolactin
- In Women: Irregular or absent periods, infertility, low libido, breast milk production outside of pregnancy.
- In Men: Low libido, erectile dysfunction, infertility, breast enlargement (rare).
- In Both: Galactorrhea (milky nipple discharge).
Regulation & Treatment
- Inhibition: Dopamine from the hypothalamus usually keeps prolactin levels low.
- Stimulation: Hormones like estrogen and TRH, as well as stress, can increase levels.
- Treatment: Often involves medications (like bromocriptine) to lower levels, especially for prolactinomas, or addressing underlying causes like hypothyroidism.
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